Benadryl Allergy Plus Congestion Interactions
There are 553 drugs known to interact with Benadryl Allergy Plus Congestion (diphenhydramine/phenylephrine), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 40 are major, 510 are moderate, and 3 are minor.
- View all 553 medications that may interact with Benadryl Allergy Plus Congestion
- View Benadryl Allergy Plus Congestion alcohol/food interactions (1)
- View Benadryl Allergy Plus Congestion disease interactions (12)
Most frequently checked interactions
View interaction reports for Benadryl Allergy Plus Congestion (diphenhydramine / phenylephrine) and the medicines listed below.
- acetaminophen
- albuterol
- amoxicillin / clavulanate
- atorvastatin
- Benadryl (diphenhydramine)
- biotin
- Flonase (fluticasone nasal)
- fluoxetine
- fluticasone nasal
- folic acid
- gabapentin
- guaifenesin
- hydroxychloroquine
- ibuprofen
- losartan
- meclizine
- melatonin
- metformin
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- montelukast
- Mucinex (guaifenesin)
- Mucinex DM (dextromethorphan / guaifenesin)
- omeprazole
- prednisone
- tizanidine
- Tylenol PM (acetaminophen / diphenhydramine)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
Benadryl Allergy Plus Congestion alcohol/food interactions
There is 1 alcohol/food interaction with Benadryl Allergy Plus Congestion (diphenhydramine / phenylephrine).
Benadryl Allergy Plus Congestion disease interactions
There are 12 disease interactions with Benadryl Allergy Plus Congestion (diphenhydramine / phenylephrine) which include:
- depression
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
More about Benadryl Allergy Plus Congestion (diphenhydramine / phenylephrine)
- Benadryl Allergy Plus Congestion consumer information
- Compare alternatives
- Pricing & coupons
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.