Acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine Interactions
There are 751 drugs known to interact with acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine, along with 15 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 106 are major, 631 are moderate, and 14 are minor.
- View all 751 medications that may interact with acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine
- View acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine alcohol/food interactions (1)
- View acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine disease interactions (15)
Most frequently checked interactions
View interaction reports for acetaminophen / dextromethorphan / diphenhydramine / guaifenesin / phenylephrine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Actifed (pseudoephedrine / triprolidine)
- Benadryl (diphenhydramine)
- Brilinta (ticagrelor)
- Dulcolax (bisacodyl)
- EPA Fish Oil (omega-3 polyunsaturated fatty acids)
- Ester-C (ascorbic acid)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Hytrin (terazosin)
- Isoptin SR (verapamil)
- K2-D3 (cholecalciferol / menaquinone)
- Milantex (aluminum hydroxide / magnesium hydroxide / simethicone)
- Mylanta (aluminum hydroxide / magnesium hydroxide / simethicone)
- Neurobion (multivitamin)
- Norvasc (amlodipine)
- Omega-3 (omega-3 polyunsaturated fatty acids)
- Panadol (acetaminophen)
- Paracetamol (acetaminophen)
- Pletal (cilostazol)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Salonpas Pain Relieving Patch (camphor / menthol / methyl salicylate topical)
- Vitamin B Complex 100 (multivitamin)
- Vitamin D3 (cholecalciferol)
Acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with acetaminophen / dextromethorphan / diphenhydramine / guaifenesin / phenylephrine.
Acetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine disease interactions
There are 15 disease interactions with acetaminophen / dextromethorphan / diphenhydramine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Banophen
Banophen is used for allergic reactions, allergic rhinitis, cold symptoms, cough, extrapyramidal ...
Benadryl Allergy
Benadryl Allergy is used for allergic reactions, allergic rhinitis, allergies, cold symptoms ...
Pseudoephedrine/triprolidine
Pseudoephedrine/triprolidine systemic is used for allergic rhinitis, cold symptoms
Echinacea
Echinacea systemic is used for cold symptoms, condylomata acuminata, herbal supplementation
Chlorpheniramine
Chlorpheniramine systemic is used for allergic reactions, allergic rhinitis, allergies, cold ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.