Excedrin PM Headache Interactions
There are 810 drugs known to interact with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine), along with 20 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 82 are major, 700 are moderate, and 28 are minor.
- View all 810 medications that may interact with Excedrin PM Headache
- View Excedrin PM Headache alcohol/food interactions (3)
- View Excedrin PM Headache disease interactions (20)
Most frequently checked interactions
View interaction reports for Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine) and the medicines listed below.
- Advil PM (diphenhydramine / ibuprofen)
- Benadryl (diphenhydramine)
- biotin
- buspirone
- cephalexin
- Claritin (loratadine)
- cyclobenzaprine
- diazepam
- doxycycline
- Excedrin Migraine (acetaminophen / aspirin / caffeine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydrocodone
- ibuprofen
- levothyroxine
- Lexapro (escitalopram)
- losartan
- magnesium citrate
- magnesium glycinate
- melatonin
- meloxicam
- methylprednisolone
- Mucinex (guaifenesin)
- omeprazole
- ondansetron
- prednisone
- sumatriptan
- trazodone
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Excedrin PM Headache alcohol/food interactions
There are 3 alcohol/food interactions with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine).
Excedrin PM Headache disease interactions
There are 20 disease interactions with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine) which include:
- alcoholism
- liver disease
- depression
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Botox
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Naproxen
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Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.