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Tri-Mili Dosage

Generic name: NORGESTIMATE 0.180mg, ETHINYL ESTRADIOL 0.035mg; NORGESTIMATE 0.215mg, ETHINYL ESTRADIOL 0.035mg; NORGESTIMATE 0.250mg, ETHINYL ESTRADIOL 0.035mg;
Dosage form: tablets

See also:

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

How to Start Tri-Mili

Tri-Mili is  available in blister pack [see How Supplied/Storage and Handling (16)]. Tri-Mili may be started using either a Day 1 start or a Sunday start (see Table 1). For the first cycle of a Sunday Start regimen, an additional method of contraception should be used until after the first  7 consecutive days of administration.

How to Take Tri-Mili


Table 1: Instructions for Administration of Tri-Mili
Starting COCs in women not currently using
hormonal contraception (Day 1 Start or Sunday Start)
 
Important:
Consider the possibility of ovulation and conception prior to initiation of this product.
 
Tablet Color:
  • Tri-Mili active tablets are white (Day 1 to Day 7), light blue (Day 8 to Day 15) and dark blue (Day 16 to Day 21).
 
  • Tri-Mili has green inactive tablets (Day 22 to Day 28).
Day 1 Start:
  • Take first active tablet without regard to meals on the first day of menses.
  • Take subsequent active tablets once daily at the same time each day for a total of 21 days.
  • Take one green inactive tablet daily for 7 days and at the same time of day that active tablets were taken.
  • Begin each subsequent pack on the same day of the week as the first cycle pack (i.e., on the day after taking the last inactive tablet)
Sunday Start:
  • Take first active tablet without regard to meals on the first Sunday after the onset of menses. Due to the potential risk of becoming pregnant, use additional non- hormonal contraception (such as condoms and spermicide) for the first seven days of the patient’s first cycle pack of Tri-Mili.
  • Take subsequent active tablets once daily at the same time each day for a total of 21 days.
  • Take one green inactive tablet daily for the following 7 days and at the same time of day that active tablets were taken.
  • Begin each subsequent pack on the same day of the week as the first cycle pack (i.e., on the Sunday after taking the last inactive tablet) and additional non-hormonal contraceptive is not needed.
 
Switching to Tri-Mili from another oral contraceptive
Start on the same day that a new pack of the previous oral contraceptive would have started.
Switching from another contraceptive method to         Tri-Mili
Start Tri-Mili:
 
● Transdermal patch
On the day when next application would have been scheduled
● Vaginal ring
On the day when next insertion would have been scheduled
● Injection
On the day when next injection would have been scheduled
● Intrauterine contraceptive
On the day of removal
If the IUD is not removed on first day of the patient’s menstrual cycle, additional non-hormonal contraceptive (such as condoms and spermicide) is needed for the first seven days of the first cycle pack. 
● Implant
On the day of removal
Complete instructions to facilitate patient counseling on proper tablet usage are located in the FDA-Approved Patient Labeling.

Starting Tri-Mili after Abortion or Miscarriage


First-trimester


  • After a first-trimester abortion or miscarriage, Tri-Mili may be started immediately. An additional method of contraception is not needed if Tri-Mili is started immediately.
  • If Tri-Mili is not started within 5 days after termination of the pregnancy, the patient should use additional non-hormonal contraception (such as condoms and spermicide) for the first seven days of her first cycle pack of Tri-Mili.

Second-trimester

  • Do not start until 4 weeks after a second-trimester abortion or miscarriage, due to the increased risk of thromboembolic disease.Start Tri-Mili, following the instructions in Table 1 for Day 1 or Sunday start, as desired. If using Sunday start, use additional non-hormonal contraception (such as condoms and spermicide) for the first seven days of the patient’s first cycle pack of Tri-Mili. [See Contraindications (4), Warnings and Precautions (5.1), and FDA-Approved Patient Labeling.]

Starting Tri-Mili after Childbirth

How to Use the Blister Pack:

There are two ways to start taking birth control pills, Sunday Start or Day 1 Start. Your healthcare professional will tell you which to use.


1. Pick the Days of the Week Sticker that starts the first day of your period. (This is the day you begin bleeding or spotting, even if it is midnight when bleeding begins.) When you have picked the right sticker, throw away the others and place the sticker on the blister pack over the preprinted days of the week and make sure it lines up with the pills.

Blister Pack 

2. Your blister pack containing 28 individually sealed pills. Note that the pills are arranged in four numbered rows of 7 pills, with the pre-printed days of the week printed above them. There are 7 white “active” pills, 7 light blue “active” pills, 7 dark blue “active” pills, and 7 green “reminder” pills. Refer to the sample of the blister pack below:

Blister Pack
 

3. After taking the last green pill, start a new blister pack the very next day no matter when your period started. You will be taking a pill every day without interruption. Anytime you start the pills later than directed, protect yourself by using another method of birth control until you have taken a pill a day for seven consecutive days. After taking the last green pill, start taking the first white pill from the blister pack the very next day.


4. Take the pills in each new package as before. Start with the white pill on row #1 and take one pill each day, left to right, until the last green pill has been taken.


Three Ways to Remember in What Order to take the Pills

 

  1. Follow the sticker with the days of the week (placed above the pills).
  2. Always go from left to right.
  3. Always finish all your pills.

Missed Tablets

Table 2: Instructions for Missed Tri-Mili Tablets
  • If one active tablet is missed in Weeks 1, 2, or 3
Take the tablet as soon as possible. Continue taking one tablet a day until the pack is finished.
  • If two active tablets are missed in Week 1 or Week 2
Take the two missed tablets as soon as possible and the next two active tablets the next day. Continue taking one tablet a day until the pack is finished. Additional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets.
  • If two active tablets are missed in the third week or three or more active tablets are missed in a row in Weeks 1, 2, or 3
Day 1 start:  Throw out the rest of the pack and start a new pack that same day.

Sunday start: Continue taking one tablet a day until Sunday, then throw out the rest of the pack and start a new pack that same day. Additional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets.

Advice in Case of Gastrointestinal Disturbances

In case of severe vomiting or diarrhea, absorption may not be complete and additional contraceptive measures should be taken. If vomiting or diarrhea occurs within 3 to 4 hours after taking an active tablet, handle this as a missed tablet [see  FDA-Approved Patient Labeling].

Tri-Mili Use for Acne

The timing of initiation of dosing with Tri-Mili  for acne should follow the guidelines for use of Tri-Mili  as an oral contraceptive. Consult the DOSAGE AND ADMINISTRATION section (2.1) for instructions.

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