Silver Sulfadiazine Topical Dosage

Medically reviewed by Drugs.com. Last updated on May 27, 2024.

Usual Adult Dose for Burns - External

Apply to the affected area 1 to 2 times a day to a thickness of about 1/16 of an inch

Comments:

• This drug should be reapplied to any areas from which it has been removed by patient activity and immediately after hydrotherapy.
• Treatment should be continued until satisfactory healing has occurred or until burn site is ready for grafting.
• This drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs.

Use: As an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns

Usual Adult Dose for Wound Sepsis

Apply to the affected area 1 to 2 times a day to a thickness of about 1/16 of an inch

Comments:

• This drug should be reapplied to any areas from which it has been removed by patient activity and immediately after hydrotherapy.
• Treatment should be continued until satisfactory healing has occurred or until burn site is ready for grafting.
• This drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs.

Use: As an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns

Renal Dose Adjustments

Renal dysfunction: Drug accumulation may occur; drug discontinuation should be weighed against therapeutic benefit being achieved

Liver Dose Adjustments

Liver dysfunction: Drug accumulation may occur; drug discontinuation should be weighed against therapeutic benefit being achieved

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active component or to any of the ingredients
• Use in pregnant women approaching or at term, premature infants, or newborns during the first 2 months of life

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Care of burn patients should be initiated promptly and includes control of shock and pain.
• Burn wounds should be cleansed and debrided prior to use of this drug,
• The burned area should be covered with this drug at all times.
• Dressings are not necessary, however, if individual patients require dressings, they may be used.

Monitoring:

• Genitourinary: Check urine for sulfa crystals in patients being treated for burn wounds involving extensive areas of the body
• Hematologic: Monitor serum sulfa concentrations in patients being treated for burn wounds involving extensive areas of the body
• Renal: Monitor renal function in patients being treated for burn wounds involving extensive areas of the body

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer