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Silver Sulfadiazine Topical Dosage

Medically reviewed on June 4, 2018.

Applies to the following strengths: 1%

Usual Adult Dose for Burns - External

Apply to the affected area 1 to 2 times a day to a thickness of about 1/16 of an inch

Comments:
-This drug should be reapplied to any areas from which it has been removed by patient activity and immediately after hydrotherapy.
-Treatment should be continued until satisfactory healing has occurred or until burn site is ready for grafting.
-This drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs.

Use: As an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns

Usual Adult Dose for Wound Sepsis

Apply to the affected area 1 to 2 times a day to a thickness of about 1/16 of an inch

Comments:
-This drug should be reapplied to any areas from which it has been removed by patient activity and immediately after hydrotherapy.
-Treatment should be continued until satisfactory healing has occurred or until burn site is ready for grafting.
-This drug should not be withdrawn from the therapeutic regimen while there remains the possibility of infection except if a significant adverse reaction occurs.

Use: As an adjunct for the prevention and treatment of wound sepsis in patients with second and third degree burns

Renal Dose Adjustments

Renal dysfunction: Drug accumulation may occur; drug discontinuation should be weighed against therapeutic benefit being achieved

Liver Dose Adjustments

Liver dysfunction: Drug accumulation may occur; drug discontinuation should be weighed against therapeutic benefit being achieved

Precautions

CONTRAINDICATIONS:
-Hypersensitivity to the active component or to any of the ingredients
-Use in pregnant women approaching or at term, premature infants, or newborns during the first 2 months of life

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Care of burn patients should be initiated promptly and includes control of shock and pain.
-Burn wounds should be cleansed and debrided prior to use of this drug,
-The burned area should be covered with this drug at all times.
-Dressings are not necessary, however, if individual patients require dressings, they may be used.

Monitoring:
-Genitourinary: Check urine for sulfa crystals in patients being treated for burn wounds involving extensive areas of the body
-Hematologic: Monitor serum sulfa concentrations in patients being treated for burn wounds involving extensive areas of the body
-Renal: Monitor renal function in patients being treated for burn wounds involving extensive areas of the body

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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