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Rilonacept Dosage

Applies to the following strength(s): 220 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Familial Cold Autoinflammatory Syndrome

Loading dose: 320 mg delivered as two, 2 mL, subcutaneous injections of 160 mg each given on the same day at two different sites.

Dosing should be continued with a once-weekly injection of 160 mg administered as a single, 2-mL, subcutaneous injection.

Rilonacept should not be given more often than once weekly.

Usual Adult Dose for Muckle Wells Snydrome

Loading dose: 320 mg delivered as two, 2 mL, subcutaneous injections of 160 mg each given on the same day at two different sites.

Dosing should be continued with a once-weekly injection of 160 mg administered as a single, 2-mL, subcutaneous injection.

Rilonacept should not be given more often than once weekly.

Usual Pediatric Dose for Familial Cold Autoinflammatory Syndrome

Greater then or equal to 12 years of age:
Loading dose: 4.4 mg/kg, up to a maximum of 320 mg, delivered as one or two subcutaneous injections with a maximum single-injection volume of 2 mL. If the initial dose is given as two injections, they should be given on the same day at two different sites.

Dosing should be continued with a once-weekly injection of 2.2 mg/kg, up to a maximum of 160 mg, administered as a single subcutaneous injection, up to 2 mL.

Rilonacept should not be given more often than once weekly.

Usual Pediatric Dose for Muckle Wells Snydrome

Greater then or equal to 12 years of age:
Loading dose: 4.4 mg/kg, up to a maximum of 320 mg, delivered as one or two subcutaneous injections with a maximum single-injection volume of 2 mL. If the initial dose is given as two injections, they should be given on the same day at two different sites.

Dosing should be continued with a once-weekly injection of 2.2 mg/kg, up to a maximum of 160 mg, administered as a single subcutaneous injection, up to 2 mL.

Rilonacept should not be given more often than once weekly.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Dosage modification is not required based on advanced age or gender.

Precautions

Sites for subcutaneous injection, such as the abdomen, thigh, or upper arm, should be rotated. Injections should never be made at sites that are bruised, red, tender, or hard.

Dialysis

Data not available

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