Meningococcal Group B Vaccine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 30, 2024.

Usual Adult Dose for Meningitis - Meningococcal

PATIENTS UP TO 25 YEARS OLD:
Two-dose schedule: 0.5 mL IM once, administered at 0 and 6 months

• If the second dose is given less than 6 months after the first dose, a third dose should be given at least 4 months after the second dose

Three-dose schedule: 0.5 mL IM once, administered at 0, 1 to 2, and 6 months

Comments:

• The dosing schedule should be determined by the patient's risk of exposure and the susceptibility to the disease.
• The dosage schedules for Bexsero and Trumenba are the same; however, it is not known if the vaccines are interchangeable.

Use: Active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B

Usual Pediatric Dose for Meningitis - Meningococcal

PATIENTS 10 YEARS AND OLDER:
Two-dose schedule: 0.5 mL IM once, administered at 0 and 6 months

• If the second dose is given less than 6 months after the first dose, a third dose should be given at least 4 months after the second dose

Three-dose schedule: 0.5 mL IM once, administered at 0, 1 to 2, and 6 months

Comments:

• The dosing schedule should be determined by the patient's risk of exposure and the susceptibility to the disease.
• The dosage schedules for Bexsero and Trumenba are the same; however, it is not known if the vaccines are interchangeable.

Use: Active immunization to prevent invasive disease caused by N meningitidis serogroup B

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Known history of severe allergic reactions (e.g., anaphylaxis) to the active component or any of the ingredients
• History of a severe allergic reaction after a previous dose of this vaccine

Safety and efficacy have not been established in patients younger than 10 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer IM in the deltoid muscle of the upper arm.

Storage requirements:

• Store refrigerated between 2C to 8C (36F to 26F); protect from light.
• Do not freeze. Discard if the vaccine has been frozen.

Reconstitution/preparation techniques:

• Shake vigorously to ensure a homogenous suspension.
• Do not use if the vaccine cannot be resuspended.

Reconstitution/preparation techniques:

• Do not dilute.
• Consult the Fact Sheet for Health Care Providers.

Patient advice:

• To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS): https://vaers.hhs.gov

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer