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Meningococcal group B vaccine Pregnancy and Breastfeeding Warnings

Meningococcal group B vaccine is also known as: Bexsero, Trumenba

Medically reviewed on November 15, 2016.

Meningococcal group B vaccine Pregnancy Warnings

Use is not recommended unless clearly needed.

US FDA pregnancy category: B

Comments:
-Vaccination should not be withheld when there is a clear risk of meningococcal exposure.

Animal studies did not show impaired fertility or harm to the fetus. There are no controlled data in human pregnancy.

To monitor the outcomes of pregnant women exposed to Bexsero(R), a pregnancy registry has been established in the US. Physicians are encouraged to register patients and pregnant women are encouraged to register themselves by calling 1-877-683-4732.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Meningococcal group B vaccine Breastfeeding Warnings

Animal studies did not show adverse reactions in mothers or offspring through day 29 of lactation; immunogenicity was seen in mothers vaccinated prior to lactation, and antibodies were detected in the offspring, but antibody levels in milk were not determined.

Use with caution

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-Evaluate risk to benefit before vaccinating women who are breast feeding.

See references

References for pregnancy information

  1. "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc, Cambridge, MA.
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Trumenba (meningococcal group B vaccine)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

References for breastfeeding information

  1. "Product Information. Trumenba (meningococcal group B vaccine)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc, Cambridge, MA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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