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Lioresal Dosage

Generic name: baclofen
Dosage form: Tablets
Drug class: Skeletal muscle relaxants

Medically reviewed by Drugs.com. Last updated on Apr 3, 2025.

The determination of optimal dosage requires individual titration. Start therapy at a low dosage and increase gradually until optimum effect is achieved (usually between 40-80 mg daily).


The following dosage titration schedule is suggested:


5 mg t.i.d. for 3 days

10 mg t.i.d. for 3 days

15 mg t.i.d. for 3 days

20 mg t.i.d. for 3 days


Thereafter additional increases may be necessary but the total daily dose should not exceed a maximum of 80 mg daily (20 mg q.i.d.).


The lowest dose compatible with an optimal response is recommended. If benefits are not evident after a reasonable trial period, patients should be slowly withdrawn from the drug (see WARNINGS Abrupt Drug Withdrawal).

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.