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Ingenol Topical Dosage

Medically reviewed by Last updated on Mar 16, 2022.

Applies to the following strengths: 0.015%; 0.05%

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Keratosis

Face and scalp: This drug should be applied to the affected area once a day for 3 consecutive days.
Trunk or extremities: This drug should be applied to the affected area once a day for 2 consecutive days.

-This drug may be applied to the affected area, up to one contiguous skin area of approximately 25 cm2 (e.g., 5 cm x 5 cm) using one unit dose tube.
-After spreading evenly over the treatment area, this drug should be allowed to dry for 15 minutes.
-Patients should wash their hands immediately after applying the drug and take care not to transfer the applied drug to other areas, including the eye.
-Patients should avoid washing and touching the treated area for a period of 6 hours after application. Following this time, patients may wash the area with a mild soap.
-This drug should not be applied orally, ophthalmically, or intravaginally.

Use: Inducer of cell death for the topical treatment of actinic keratosis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:
-This drug is for external use only; not for oral, ophthalmic, vaginal, or anal use.
-This drug should be avoided in the periocular area.
-This drug should not be applied around the mouth and lips.

Storage requirements:
-This drug should be stored in a refrigerator at 36F to 46F (2C to 8C); excursions permitted between 32F to 59F (0C to 15C).
-Protect from freezing.
-Tubes should be discarded after first opening.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.