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Icosapent Dosage

Medically reviewed on March 2, 2017.

Applies to the following strengths: 1 g; 0.5 g

Usual Adult Dose for Hypertriglyceridemia

4 grams per day taken as 2 capsules orally twice daily with food

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels should be monitored periodically in patients with hepatic impairment.

Patient receiving icosapent should be periodically monitored for prolonged bleeding times.

Though no overall differences in the safety or effectiveness were observed between older (65 years and over) and younger patients, greater sensitivity of older individuals cannot be ruled out.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).


Data not available

Other Comments

Prior to initiating icosapent, medical problems such as diabetes mellitus, hypothyroidism, and alcohol intake should be controlled. In addition, medications known to exacerbate hypertriglyceridemia (such as beta blockers, thiazides, estrogens) should be discontinued or changed, if possible.

Before initiating icosapent, patients should be placed on a lipid lowering diet and exercise regimen.

Icosapent capsules should be swallowed whole and taken with or following a meal.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.