Dirithromycin Dosage

Usual Adult Dose for Bronchitis

Moraxella Catarrhalis or Streptococcus Pneumoniae: 500 mg orally once a day for 7 days.

Usual Adult Dose for Tonsillitis/Pharyngitis

Streptococcus Pyogenes: 500 mg orally once a day for 10 days.

Usual Adult Dose for Skin or Soft Tissue Infection

Staphylococcus Aureus (methicillin-susceptible): 500 mg orally once a day for 7 days.

Usual Adult Dose for Legionella Pneumonia

500 mg orally once a day for 14 days.

Usual Adult Dose for Mycoplasma Pneumonia

500 mg orally once a day for 14 days.

Usual Adult Dose for Pneumonia

500 mg orally once a day for 14 days.

Usual Adult Dose for Otitis Media

500 mg orally once a day for 10 days.

Usual Adult Dose for Upper Respiratory Tract Infection

500 mg orally once a day for 7 days.

Usual Pediatric Dose for Bronchitis

Child > 12 years: Moraxella Catarrhalis or Streptococcus Pneumoniae: 500 mg orally once a day for 7 days.

Usual Pediatric Dose for Pneumonia

Child > 12 years: Legionella Pneumophila, Mycoplasma Pneumoniae, or Streptococcus Pneumoniae: 500 mg orally once a day for 14 days.

Usual Pediatric Dose for Tonsillitis/Pharyngitis

Child > 12 years: Streptococcus Pyogenes: 500 mg orally once a day for 10 days.

Usual Pediatric Dose for Skin or Soft Tissue Infection

Child > 12 years: Staphylococcus Aureus (methicillin-susceptible): 500 mg orally once a day for 7 days.

Liver Dose Adjustments

Patients with severe liver disease may require every other day dosing.

Dialysis

Hemo- or peritoneal dialysis have not been established as beneficial for an overdose of dirithromycin.

Other Comments

Dirithromycin should be given with food or within 1 hour of having eaten.