Clindamycin / Tretinoin Topical Dosage

Medically reviewed by Drugs.com. Last updated on Jul 7, 2025.

Usual Adult Dose for Acne

At bedtime, squeeze a pea-sized amount of medication into one fingertip, dot it onto the chin, cheeks, nose, and forehead, and then gently rub over the entire face.

Comments: Avoid the eyes, lips, and mucous membranes. This medication is not for oral, ophthalmic, intranasal or intravaginal use.

Use: Topical treatment of acne vulgaris in patients 12 years or older.

Usual Pediatric Dose for Acne

Patients 12 years through 18 years: At bedtime, squeeze a pea-sized amount of medication into one fingertip, dot it onto the chin, cheeks, nose, and forehead, and then gently rub over the entire face.

Comments: Avoid the eyes, lips, and mucous membranes. This medication is not for oral, ophthalmic, intranasal or intravaginal use.

Use: Topical treatment of acne vulgaris in patients 12 years or older.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Regional enteritis, ulcerative colitis, or history of antibiotic-associated colitis

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Advice patients to gently washed the face with a mild soap and warm water at bedtime.
• Advice patients to apply medication as a thin layer over the entire face (excluding the eyes and lips after patting the skin dry.
• After the application the patient should wash hands.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
• Advise patient to apply a sunscreen every morning and to reapply over the course of the day as needed.
• Advise patients to avoid exposure to sunlight, sunlamp, ultraviolet light, and other medicines that may increase sensitivity to sunlight.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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