Cephalothin Dosage
Applies to the following strengths: 1 g; 2 g; 1 g/50 mL; 2 g/50 mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Skin or Soft Tissue Infection
Uncomplicated infections: 500 mg to 1 g IV or IM every 4 to 6 hours.
Severe infections: 1 g IV or IM every 6 hours or 500 mg every 4 hours.
Life-threatening infections: 2 g IV or IM every 4 hours.
Usual Adult Dose for Surgical Prophylaxis
Preoperative: 1 to 2 g IV 30 to 60 minutes prior to incision.
Intraoperative: 1 to 2 g IV during surgery.
Postoperative: 1 to 2 g IV every 6 hours for up to 24 hours.
Usual Pediatric Dose for Surgical Prophylaxis
Preoperative: 20 to 30 mg/kg IV 30 to 60 minutes prior to incision.
Intraoperative: 20 to 30 mg/kg IV during surgery.
Postoperative: 20 to 30 mg/kg IV every 6 hours for up to 24 hours.
Renal Dose Adjustments
CrCl < 2 mL/min: Loading dose of 1 to 2 g, then maximum dose 0.5 g IV every 8 hours.
CrCl 2 to 10 mL/min: Loading dose of 1 to 2 g, then maximum dose 0.5 g IV every 6 hours.
CrCl 10 to 25 mL/min: Loading dose of 1 to 2 g, then maximum dose 1 g IV every 6 hours.
CrCl 25 to 50 mL/min: Loading dose of 1 to 2 g, then maximum dose 1.5 g IV every 6 hours.
CrCl 50 to 80 mL/min: Maximum dose 2 g IV every 6 hours.
Dialysis
Cephalothin has been added to peritoneal dialysis fluid up to 6 mg/100 mL and instilled throughout an entire dialysis.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about cephalothin
- Side Effects
- During Pregnancy
- Drug Interactions
- 1 Review
- Drug class: first generation cephalosporins
