Calcifediol Dosage
Medically reviewed by Drugs.com. Last updated on Feb 3, 2025.
Applies to the following strengths: 20 mcg; 50 mcg; 30 mcg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Hypocalcemia
Initial dose: 50 mcg orally once a day or 100 mcg orally every other day.
Maintenance dose: May increase by 20 mcg/dose at 4 week intervals.
Usual Adult Dose for Renal Osteodystrophy
Initial dose: 50 mcg orally once a day or 100 mcg orally every other day.
Maintenance dose: May increase by 20 mcg/dose at 4 week intervals.
Renal Dose Adjustments
No adjustments recommended, however, patients with renal insufficiency are more prone to the development of hypercalcemia and should by closely monitored.
Liver Dose Adjustments
Data not available
Dose Adjustments
Some patients may respond to as little as 20 mcg every other day. Most patients respond to 50 to 100 mcg once a day or 100 to 200 mcg every other day.
Precautions
Calcifediol should be withheld if hypercalcemia develops.
Dialysis
Vitamin D and its metabolites are not dialyzable.
Other Comments
Patients should receive adequate calcium during calcifediol therapy. Serum calcium should be monitored once to twice a week during dosage titration, and approximately once a month after stabilization of the dosage.
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