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Calcifediol Dosage

Medically reviewed on June 7, 2017.

Applies to the following strengths: 20 mcg; 50 mcg; 30 mcg

Usual Adult Dose for Hypocalcemia

Initial dose: 50 mcg orally once a day or 100 mcg orally every other day.
Maintenance dose: May increase by 20 mcg/dose at 4 week intervals.

Usual Adult Dose for Renal Osteodystrophy

Initial dose: 50 mcg orally once a day or 100 mcg orally every other day.
Maintenance dose: May increase by 20 mcg/dose at 4 week intervals.

Renal Dose Adjustments

No adjustments recommended, however, patients with renal insufficiency are more prone to the development of hypercalcemia and should by closely monitored.

Liver Dose Adjustments

Data not available

Dose Adjustments

Some patients may respond to as little as 20 mcg every other day. Most patients respond to 50 to 100 mcg once a day or 100 to 200 mcg every other day.

Precautions

Calcifediol should be withheld if hypercalcemia develops.

Dialysis

Vitamin D and its metabolites are not dialyzable.

Other Comments

Patients should receive adequate calcium during calcifediol therapy. Serum calcium should be monitored once to twice a week during dosage titration, and approximately once a month after stabilization of the dosage.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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