Augmentin ES-600 Dosage
Medically reviewed by Drugs.com. Last updated on Nov 23, 2021.
Generic name: AMOXICILLIN 600mg in 5mL, CLAVULANATE POTASSIUM 42.9mg in 5mL
Dosage form: powder, for oral suspension
AUGMENTIN ES-600 Powder for Oral Suspension, does not contain the same amount of clavulanic acid (as the potassium salt) as any of the other suspensions of AUGMENTIN. AUGMENTIN ES-600 Powder for Oral Suspension contains 42.9 mg of clavulanic acid per 5 mL, whereas the 200 mg/5 mL suspension of AUGMENTIN contains 28.5 mg of clavulanic acid per 5 mL and the 400 mg/5 mL suspension contains 57 mg of clavulanic acid per 5 mL. Therefore, the 200 mg/28.5 mg/5 mL and 400 mg/57 mg/5 mL suspensions of AUGMENTIN should not be substituted for AUGMENTIN ES-600 Powder for Oral Suspension as they are not interchangeable.
Dosage:
Pediatric patients 3 months and older:
Based on the amoxicillin component (600 mg/5 mL), the recommended dose of AUGMENTIN ES-600 Powder for Oral Suspension is 90 mg/kg/day divided every 12 hours, administered for 10 days (see chart below).
| Body Weight (kg) | Volume of AUGMENTIN ES-600 Powder for Oral Suspension providing 90 mg/kg/day |
|---|---|
| 8 | 3.0 mL twice daily |
| 12 | 4.5 mL twice daily |
| 16 | 6.0 mL twice daily |
| 20 | 7.5 mL twice daily |
| 24 | 9.0 mL twice daily |
| 28 | 10.5 mL twice daily |
| 32 | 12.0 mL twice daily |
| 36 | 13.5 mL twice daily |
Pediatric patients weighing 40 kg and more:
Experience with AUGMENTIN ES-600 Powder for Oral Suspension in this group is not available.
Adults:
Experience with AUGMENTIN ES-600 Powder for Oral Suspension in adults is not available and adults who have difficulty swallowing should not be given AUGMENTIN ES-600 Powder for Oral Suspension in place of the 500-mg or 875-mg tablet of AUGMENTIN.
Hepatically impaired patients should be dosed with caution and hepatic function monitored at regular intervals. (See WARNINGS.)
Directions for Mixing Oral Suspension:
Prepare a suspension at time of dispensing as follows: Tap bottle until all the powder flows freely. Add approximately 2/3 of the total amount of water for reconstitution (see table below) and shake vigorously to suspend powder. Add remainder of the water and again shake vigorously.
| Bottle Size | Amount of Water Required for Reconstitution |
| 75 mL | 70 mL |
| 125 mL | 110 mL |
| 200 mL | 180 mL |
Each teaspoonful (5 mL) will contain 600 mg amoxicillin as the trihydrate and 42.9 mg of clavulanic acid as the potassium salt.
NOTE: SHAKE ORAL SUSPENSION WELL BEFORE USING.
Information for the Pharmacist:
For patients who wish to alter the taste of AUGMENTIN ES-600 Powder for Oral Suspension, immediately after reconstitution 1 drop of FLAVORx™ (apple, banana cream, bubble gum, cherry, or watermelon flavor) may be added for every 5 mL of AUGMENTIN ES-600 Powder for Oral Suspension. The resulting suspension is stable for 10 days under refrigeration. Stability of AUGMENTIN ES-600 Powder for Oral Suspension when mixed with other flavors distributed by FLAVORx has not been evaluated for flavors other than the 5 flavors listed above.
Administration:
To minimize the potential for gastrointestinal intolerance, AUGMENTIN ES-600 Powder for Oral Suspension should be taken at the start of a meal. Absorption of clavulanate potassium may be enhanced when AUGMENTIN ES-600 Powder for Oral Suspension is administered at the start of a meal.
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More about Augmentin ES-600 (amoxicillin / clavulanate)
- Side effects
- Drug interactions
- During pregnancy
- Reviews (2)
- Generic availability
- Drug class: beta-lactamase inhibitors
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