Skip to main content

Allopurinol / Lesinurad Dosage

Applies to the following strengths: 200 mg-200 mg; 300 mg-200 mg

Usual Adult Dose for Gout

Initial dose:


Comments:

Use: Treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with medically appropriate doses of allopurinol alone

Renal Dose Adjustments

Prior to initiation:


During treatment:

Liver Dose Adjustments

Mild to moderate liver dysfunction (Child-Pugh Classes A and B): No adjustment recommended.
Severe liver dysfunction (Child-Pugh Class C): Not recommended.

Dose Adjustments

Patients taking azathioprine or mercaptopurine:

Precautions

US BOXED WARNINGS:
RISK OF ACUTE RENAL FAILURE:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Contraindicated

Other Comments

Administration advice:


General:

Monitoring:

Patient advice:

More about allopurinol / lesinurad

Patient resources

Other brands

Duzallo

Professional resources

Other brands

Duzallo

Related treatment guides

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.