Acetaminophen / Pseudoephedrine Dosage

Medically reviewed on January 25, 2019.

Usual Adult Dose for Sinus Symptoms

2 tablets or capsules (325 mg-30 mg or 500 mg-30 mg strength) orally every 4 to 6 hours as needed, no more than four times a day.

Usual Pediatric Dose for Fever

Infant drops (80 mg-7.5 mg/0.8 mL):
2 to 3 years or 24 to 35 lbs: 1.6 mL (2 droppersful) orally every 4 to 6 hours as needed, no more than four times a day.

Children's liquid (160 mg-15 mg/5 mL):
2 to 3 years or 24 to 35 lbs: 5 mL (1 teaspoonful) orally every 4 to 6 hours as needed, no more than four times a day.
4 to 5 years or 36 to 47 lbs: 7.5 mL (1 1/2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
6 to 8 years or 48 to 59 lbs: 10 mL (2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
9 to 10 years or 60 to 71 lbs: 12.5 mL (2 1/2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
11 years or 72 to 95 lbs: 15 mL (3 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.

Children's Chewable tablets (160 mg-15 mg):
2 to 5 years: 1 tablets orally every 4 to 6 hours as needed, no more than four times a day.
6 to 11 years: 2 tablets orally every 4 to 6 hours as needed, no more than four times a day.

Usual Pediatric Dose for Sinus Symptoms

Infant drops (80 mg-7.5 mg/0.8 mL):
2 to 3 years or 24 to 35 lbs: 1.6 mL (2 droppersful) orally every 4 to 6 hours as needed, no more than four times a day.

Children's liquid (160 mg-15 mg/5 mL):
2 to 3 years or 24 to 35 lbs: 5 mL (1 teaspoonful) orally every 4 to 6 hours as needed, no more than four times a day.
4 to 5 years or 36 to 47 lbs: 7.5 mL (1 1/2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
6 to 8 years or 48 to 59 lbs: 10 mL (2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
9 to 10 years or 60 to 71 lbs: 12.5 mL (2 1/2 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.
11 years or 72 to 95 lbs: 15 mL (3 teaspoonsful) orally every 4 to 6 hours as needed, no more than four times a day.

Children's Chewable tablets (160 mg-15 mg):
2 to 5 years: 1 tablets orally every 4 to 6 hours as needed, no more than four times a day.
6 to 11 years: 2 tablets orally every 4 to 6 hours as needed, no more than four times a day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

Other Comments

In pediatric patients, acetaminophen-pseudoephedrine should preferably be dosed according to body weight.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer