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Acetaminophen / Dextromethorphan / Phenylephrine Dosage

Applies to the following strengths: 325 mg-10 mg-5 mg; 325 mg-10 mg-5 mg/15 mL; 650 mg-20 mg-10 mg; 500 mg-20 mg-10 mg; 650 mg-20 mg-10 mg/30 mL; 160 mg-5 mg-2.5 mg/5 mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cold Symptoms

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg oral capsule:
2 capsules orally every 4 hours. Do not exceed 8 capsules in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg oral tablet:
2 tablets orally every 4 hours. Do not exceed 12 tablets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 650 mg-20 mg-10 mg/ 30 mL oral liquid:
30 mL orally every 4 hours. Do not exceed 180 mL in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg/15 mL oral syrup:
30 mL orally every 4 hours. Do not exceed 180 mL in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-20 mg-10 mg oral powder for reconstitution:
Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 650 mg-20 mg-10 mg oral powder for reconstitution:
Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 10 to 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 500 mg-20 mg-10 mg oral powder for reconstitution:
Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 10 to 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Usual Pediatric Dose for Cold Symptoms

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg oral capsule:
6 to 11 yrs: 1 capsule orally every 4 hours. Do not exceed 4 capsules in 24 hours.
12 years and older: 2 capsules orally every 4 hours. Do not exceed 8 capsules in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg oral tablet:
12 years and older: 2 tablets orally every 4 hours. Do not exceed 12 tablets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 650 mg-20 mg-10 mg/ 30 mL oral liquid:
12 years and older: 30 mL orally every 4 hours. Do not exceed 180 mL in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-10 mg-5 mg/15 mL oral syrup:
12 years and older: 30 mL orally every 4 hours. Do not exceed 180 mL in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 325 mg-20 mg-10 mg oral powder for reconstitution:
12 years and older: Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 650 mg-20 mg-10 mg oral powder for reconstitution:
12 years and older: Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 10 to 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Acetaminophen/dextromethorphan/phenylephrine 500 mg-20 mg-10 mg oral powder for reconstitution:
12 years and older: Dissolve contents of one packet in 8 ounces of hot water. Consume entire drink within 10 to 15 minutes.
1 packet orally every 4 hours. Do not exceed 6 packets in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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