Obagi (tretinoin topical) Disease Interactions
There are 2 disease interactions with Obagi (tretinoin topical):
Retinoid/Retinoid-Like Topical (Includes Obagi) ↔ Eczema
Severe Potential Hazard, High plausibility
Applies to: Eczema
Topical retinoids may cause severe irritation on eczematous skin. Therapy with topical retinoids should be avoided on abraded or eczematous skin.
References
- "Product Information. Differin (adapalene topical)." Galderma Laboratories Inc, Fort Worth, TX.
- "Product Information. Tazorac (tazarotene topical)." Allergan Inc, Irvine, CA.
- "Product Information. Retin-A (tretinoin)." Ortho Pharmaceutical Corporation, Raritan, NJ.
Retinoid/Retinoid-Like Topical (Includes Obagi) ↔ Sunburn
Moderate Potential Hazard, High plausibility
Applies to: Sunburn
Retinoid-like products can cause extreme irritation when applied to sunburned skin. Patients with sunburn should be cautioned not to use retinoid-like acne products until fully recovered, and to avoid prolonged exposure to sunlight (including sunlamps) and use sunscreen/protective clothing during treatment with these products.
References
- "Product Information. Differin (adapalene topical)." Galderma Laboratories Inc, Fort Worth, TX.
- Rosenbluth M "Adverse reaction to retin-A." J Am Dent Assoc 119 (1989): 346
- "Product Information. Tazorac (tazarotene topical)." Allergan Inc, Irvine, CA.
Obagi (tretinoin topical) drug Interactions
There are 33 drug interactions with Obagi (tretinoin topical)
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2017 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
