Granix (tbo-filgrastim) Disease Interactions
There are 2 disease interactions with Granix (tbo-filgrastim):
Csf (Includes Granix) ↔ Glomerulonephritis
Severe Potential Hazard, Moderate plausibility
Applies to: Renal Dysfunction
Although it has been reported that renal dysfunction has no effect on the pharmacokinetics of colony stimulating factors (CSF), filgrastim and pegfilgrastim may cause glomerulonephritis. Symptoms include swelling of the face or ankles, dark colored urine, or blood in the urine, or a decrease in urine production. Advise patients to report signs or symptoms of glomerulonephritis immediately. Monitoring of patients with renal dysfunction is recommended.
Tbo-Filgrastim (Includes Granix) ↔ Tumor Growth
Moderate Potential Hazard, Moderate plausibility
Applies to: Myelodysplastic Disease
Tbo-filgrastim can act as a growth factor for any tumor type, including myeloid malignancies and myelodysplasia disease, diseases for which its use has not been approved.
Granix (tbo-filgrastim) drug Interactions
There are 131 drug interactions with Granix (tbo-filgrastim)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
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