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Granix Side Effects

Generic Name: tbo-filgrastim

Note: This document contains side effect information about tbo-filgrastim. Some of the dosage forms listed on this page may not apply to the brand name Granix.

For the Consumer

Applies to tbo-filgrastim: subcutaneous solution

Along with its needed effects, tbo-filgrastim (the active ingredient contained in Granix) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking tbo-filgrastim:

More Common

  • Bone pain


Incidence Not Known

  • Bloody or cloudy urine
  • chest pain or tightness
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, itching, or skin rash
  • pain in the upper left part of the stomach or at the tip of the left shoulder
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • trouble breathing
  • unusual weakness
  • weight gain

Some side effects of tbo-filgrastim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence Not Known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to tbo-filgrastim: subcutaneous solution


Common (1% to 10%): Bone pain (3.4%)[Ref]


Uncommon (0.1% to 1%): Leukocytosis (less than 1%)[Ref]


Postmarketing reports: Sweet's syndrome (acute febrile neutrophilic dermatosis)[Ref]


Postmarketing reports: Diarrhea[Ref]


Postmarketing reports: Asthenia, fatigue[Ref]


1. "Product Information. Granix (tbo-filgrastim)." Teva Pharmaceuticals USA, North Wales, PA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.