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Tbo-Filgrastim Dosage

Medically reviewed on February 15, 2017.

Applies to the following strengths: 300 mcg/0.5 mL; 480 mcg/0.8 mL

Usual Adult Dose for Neutropenia Associated with Chemotherapy

5 mcg/kg/day as a single daily subcutaneous bolus injection.

Duration of therapy: Daily dosing should continue until the expected neutrophil nadir is
passed and the neutrophil count has recovered to the normal range.

-Avoid administration during the period 24 hours before through 24 hours after the administration of cytotoxic chemotherapy.
-Monitor complete blood count (CBC) prior to chemotherapy and twice per week until recovery.

Use: Reduction in the duration of severe neutropenia in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a clinically significant incidence of febrile neutropenia.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for dosing related precautions.


Data not available

Other Comments

Administration advice: The manufacturer's product information should be consulted.
Reconstitution/preparation techniques: The manufacturer's product information should be consulted.
Storage requirements: Refrigerate at 36F to 46F (2C to 8C). Protect from light. Avoid shaking.

Within its shelf life, the product may be removed from 36F to 46F (2C to 8C) storage for a single period of up to 5 days between 73F to 81F (23C to 27C). If not used within 5 days, the product may be returned to the refrigerator through the package expiration date.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.