Bridion (sugammadex) Disease Interactions
There are 3 disease interactions with Bridion (sugammadex):
Sugammadex (Includes Bridion) ↔ bleeding
Moderate Potential Hazard, Moderate plausibility. Applies to: Coagulation Defect
Sugammadex increases the risk of coagulopathies and bleeding. It is recommended to carefully monitor coagulation parameters in patients with known coagulopathies being treated with therapeutic anticoagulation, receiving thromboprophylaxis drugs, other than heparin and low molecular weight heparin.
Sugammadex (Includes Bridion) ↔ liver dysfunction
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Sugammadex is not metabolized nor excreted by the liver. It is recommended to use caution when administering sugammadex to patients with hepatic impairment as no dedicated trials have been conducted in these patients.
Sugammadex (Includes Bridion) ↔ renal impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction
Sugammadex is substantially excreted by the kidney, and the risk of toxic reactions to this drug may be higher in patients with impaired renal function. Dosage adjustment is not required in patients with mild to moderate renal impairment. Sugammadex is not recommended for use in patients with severe renal impairment, including those requiring dialysis, due to insufficient safety information combined with the prolonged and increased overall exposure in these patients.
Bridion (sugammadex) drug interactions
There are 28 drug interactions with Bridion (sugammadex)
More about Bridion (sugammadex)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous central nervous system agents
- FDA Approval History
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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