Sotatercept Disease Interactions
There are 2 disease interactions with sotatercept.
Sotatercept (applies to sotatercept) bleeding
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia
Sotatercept may cause severe thrombocytopenia and increase the risk of bleeding. Do not initiate treatment with sotatercept in patients with platelet counts below 50,000/mm3. Do not administer sotatercept in patients who are experiencing serious bleeding.
Sotatercept (applies to sotatercept) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The effect of hepatic impairment on the pharmacokinetics of sotatercept has not been studied.
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Sotatercept drug interactions
There are 2 drug interactions with sotatercept.
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- Drug class: agents for pulmonary hypertension
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
