Sotatercept Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.
Applies to sotatercept: parenteral powder for injection.
Side effects include:
Most common adverse effects (≥10%): headache, epistaxis, rash, telangiectasia, diarrhea, dizziness, erythema.
For healthcare professionals
Applies to sotatercept: subcutaneous kit.
General adverse events
The most common adverse reactions occurring in 10% of patients or greater included increased hemoglobin, decreased platelets, headache, epistaxis, rash, telangiectasia, diarrhea, dizziness, and erythema.[Ref]
Cardiovascular
- Frequency not reported: Increased blood pressure
Dermatologic
- Very common (10% or more): Rash (20.2%), telangiectasia (16.6%), erythema (13.5%)
Gastrointestinal
- Very common (10% or more): Diarrhea (15.3%)
Hematologic
- Very common (10% or more): Increased hemoglobin (53%), decreased platelets (25%)
- Common (1% to 10%): Serious bleeding (e.g., gastrointestinal, intracranial hemorrhage), severe thrombocytopenia (platelet count less than 50,000/mm3)
Immunologic
- Very common (10% or more): Antidrug antibodies (27%)
- Common (1% to 10%): Neutralizing antibodies positive
Nervous system
- Very common (10% or more): Headache (24.5%), dizziness (14.7%)
Respiratory
- Very common (10% or more): Epistaxis (22.1%)
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References
1. (2024) "Product Information. Winrevair (sotatercept)." Merck & Co., Inc
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Further information
Sotatercept side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.