Adagen Disease Interactions
There are 2 disease interactions with Adagen (pegademase bovine).
Pegademase bovine (applies to Adagen) bone marrow transplantation
Major Potential Hazard, Moderate plausibility.
The use of pegademase bovine is contraindicated as preparatory or support therapy for bone marrow transplantation.
Pegademase bovine (applies to Adagen) platelet disorders
Major Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Coagulation Defect, Thrombocytopathy
Pegademase bovine should be used with caution in patients with thrombocytopenia. This agent should not be used in patients with severe thrombocytopenia. Pegademase is administered by IM injection and the risk of bleeding is increased in the presence of severe thrombocytopenia. Therapy with pegademase bovine should be administered cautiously in patients with coagulation or platelet function disorders.
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Adagen drug interactions
There are 2 drug interactions with Adagen (pegademase bovine).
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- During pregnancy
- Drug class: other immunostimulants
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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