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Pegademase Bovine use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Nov 29, 2021.

Drugs containing Pegademase Bovine: Adagen

Pegademase Bovine Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of pegademase bovine during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Polyethylene glycol is not excreted into breastmilk.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Clowse ME, Förger F, Hwang C, et al. Minimal to no transfer of certolizumab pegol into breast milk: Results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. Ann Rheum Dis. 2017;76:1890–6. [PMC free article: PMC5705850] [PubMed: 28814432]

Substance Identification

Substance Name

Pegademase Bovine

CAS Registry Number

130167-68-9

Drug Class

Breast Feeding

Lactation

Enzymes

Enzyme Replacement Therapy

Adenosine Deaminase

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Further information

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