Pegademase bovine Pregnancy and Breastfeeding Warnings
Pegademase bovine is also known as: Adagen
Medically reviewed by Drugs.com. Last updated on Dec 7, 2020.
Pegademase bovine Pregnancy Warnings
Animal reproduction studies and fertility impairment studies have not been conducted. There are no controlled data in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This drug should be used during pregnancy only if clearly needed.
US FDA pregnancy category: C
Pegademase bovine Breastfeeding Warnings
Caution is recommended.
Excreted into human milk: Unknown
Excreted into animal milk: Data not available
Comments: Since this drug is a large protein molecule, the amount in milk is expected to be very low and absorption is doubtful because it's likely destroyed in the child's gastrointestinal tract.
References for pregnancy information
- "Product Information. Adagen (pegademase bovine)." Enzon Inc, Piscataway, NJ.
References for breastfeeding information
- United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
- "Product Information. Adagen (pegademase bovine)." Enzon Inc, Piscataway, NJ.
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Further information
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