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Pegademase bovine Pregnancy and Breastfeeding Warnings

Brand names: Adagen

Pegademase bovine Pregnancy Warnings

Animal reproduction studies and fertility impairment studies have not been conducted. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: C

See references

Pegademase bovine Breastfeeding Warnings

Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: Since this drug is a large protein molecule, the amount in milk is expected to be very low and absorption is doubtful because it's likely destroyed in the child's gastrointestinal tract.

See references

References for pregnancy information

  1. Product Information. Adagen (pegademase bovine). Enzon Inc. 2001;PROD.

References for breastfeeding information

  1. Product Information. Adagen (pegademase bovine). Enzon Inc. 2001;PROD.
  2. United States National Library of Medicine. Toxnet. Toxicology Data Network. 2013.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.