Niacinamide/tretinoin topical Disease Interactions
There are 2 disease interactions with niacinamide / tretinoin topical.
Retinoid/retinoid-like topical (applies to niacinamide/tretinoin topical) eczema
Major Potential Hazard, High plausibility.
Topical retinoids may cause severe irritation on eczematous skin. Therapy with topical retinoids should be avoided on abraded or eczematous skin.
References
- "Product Information. Retin-A (tretinoin)." Ortho McNeil Pharmaceutical PROD (2001):
- "Product Information. Differin (adapalene topical)." Galderma Laboratories Inc PROD (2001):
- "Product Information. Tazorac (tazarotene topical)." Allergan Inc PROD (2001):
Retinoid/retinoid-like topical (applies to niacinamide/tretinoin topical) sunburn
Moderate Potential Hazard, High plausibility.
Retinoid-like products can cause extreme irritation when applied to sunburned skin. Patients with sunburn should be cautioned not to use retinoid-like acne products until fully recovered, and to avoid prolonged exposure to sunlight (including sunlamps) and use sunscreen/protective clothing during treatment with these products.
References
- Rosenbluth M "Adverse reaction to retin-A." J Am Dent Assoc 119 (1989): 346
- "Product Information. Retin-A (tretinoin)." Ortho McNeil Pharmaceutical PROD (2001):
- "Product Information. Differin (adapalene topical)." Galderma Laboratories Inc PROD (2001):
- "Product Information. Tazorac (tazarotene topical)." Allergan Inc PROD (2001):
Niacinamide/tretinoin topical drug interactions
There are 12 drug interactions with niacinamide / tretinoin topical.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.