Revia (naltrexone) Disease Interactions
There is 1 disease interaction with Revia (naltrexone):
Opiate Antagonists (Includes Revia) ↔ Hepatic/Renal Dysfunction
Moderate Potential Hazard, Moderate plausibility
Applies to: Renal Dysfunction, Liver Disease
Opiate antagonists are metabolized by the liver (naltrexone to an active metabolite) and eliminated by the kidney. Hepatic and renal impairment may reduce the metabolism and clearance of opiate antagonists. Dosage adjustment for single dose administration is not necessary, however, repeated doses in patients with hepatic and/or renal dysfunction may require adjustment.
References
- "Product Information. Narcan (naloxone)." DuPont Pharmaceuticals, Wilmington, DE.
- "Product Information. Revex (nalmefene)." Ohmeda Pharmaceutical Products Division, Liberty Corner, NJ.
Revia (naltrexone) drug Interactions
There are 518 drug interactions with Revia (naltrexone)
Revia (naltrexone) alcohol/food Interactions
There is 1 alcohol/food interaction with Revia (naltrexone)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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