Faslodex Disease Interactions
There are 2 disease interactions with Faslodex (fulvestrant).
Fulvestrant (applies to Faslodex) hepatic dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Fulvestrant is metabolized primarily in the liver. A dose of fulvestrant 250 mg is recommended in patients with moderate hepatic impairment (Child-Pugh class B). Care is recommended when using fulvestrant in patients with severe hepatic impairment (Child-Pugh class C) as the agent has not been studied in these patients.
Fulvestrant (applies to Faslodex) bleeding
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia
Fulvestrant injection is administered intramuscularly and site related events have been reported. It is recommended to use caution in patients with bleeding diatheses, thrombocytopenia, or anticoagulant use. In addition, caution should be taken while administering fulvestrant injection at the dorsogluteal injection site due to the proximity of the underlying sciatic nerve.
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Faslodex drug interactions
There are 3 drug interactions with Faslodex (fulvestrant).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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