Dyclonine/menthol topical Disease Interactions
There is 1 disease interaction with dyclonine / menthol topical.
Dyclonine topical (applies to dyclonine/menthol topical) conduction dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Shock, Heart Block
Dyclonine is absorbed rapidly through intact skin and mucosal membranes following topical administration. Prolonged exposure, large doses, frequent applications and/or use on compromised skin or mucosa can produce systemic toxicity. Cardiovascular adverse effects include depression of myocardium, hypotension, bradycardia, and cardiac arrest. Therapy with dyclonine topical should be administered cautiously in patients with shock, sinus bradyarrhythmia, or severe heart block. The recommended dosage should not be exceeded.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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