Inapsine (droperidol) Disease Interactions
There are 4 disease interactions with Inapsine (droperidol):
Droperidol (applies to Inapsine) cardiovascular
Major Potential Hazard, Moderate plausibility. Applicable conditions: Long QT Syndrome, Electrolyte Abnormalities, Hypokalemia, Magnesium Imbalance
Cases of QT prolongation and/or torsade de pointes have been reported in patients receiving droperidol at doses at or below recommended doses. Extreme caution is recommended when using this agent in patients with risk factors for development of prolonged QT syndrome, such as clinically significant bradycardia, any clinically significant cardiac disease, treatment with Class I and Class III antiarrhythmics, treatment with monoamine oxidase inhibitors (MAOI's), concomitant treatment with other drug products known to prolong the QT interval, and electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs that may cause electrolyte imbalance. It is advisable that all patients undergo a 12-lead ECG prior to administration to determine if a prolonged QT interval (i.e., QTc greater than 440 msec. for males or 450 msec. for females) is present. If there is a prolonged QT interval, droperidol should not be administered.
Droperidol (applies to Inapsine) QT prolongation
Major Potential Hazard, Moderate plausibility. Applicable conditions: Long QT Syndrome
The use of droperidol is contraindicated in patients with known or suspected QT prolongation (i.e., QTc interval greater than 440 msec. for males or 450 msec. for females), including those patients with congenital long QT syndrome.
Droperidol (applies to Inapsine) hepatic/renal dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Droperidol should be administered with caution in patients with liver and kidney dysfunction because of the importance of these organs in the metabolism and excretion of drugs.
Droperidol (applies to Inapsine) pheochromocytoma
Moderate Potential Hazard, Moderate plausibility.
Droperidol should be used with caution in patients with diagnosed or suspected pheochromocytoma as severe hypertension and tachycardia have been observed after its administration.
Inapsine (droperidol) drug interactions
There are 489 drug interactions with Inapsine (droperidol)
Inapsine (droperidol) alcohol/food interactions
There is 1 alcohol/food interaction with Inapsine (droperidol)
More about Inapsine (droperidol)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- 3 Reviews
- Generic Availability
- Drug class: miscellaneous central nervous system agents
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|