Quviviq Disease Interactions
There are 5 disease interactions with Quviviq (daridorexant).
Daridorexant (applies to Quviviq) narcolepsy
Major Potential Hazard, Moderate plausibility.
Daridorexant is contraindicated in patients with narcolepsy.
Daridorexant (applies to Quviviq) alcohol/drug abuse
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Alcoholism, Drug Abuse/Dependence
Patients with a history of abuse or addiction to alcohol or other substances may be at increased risk for abuse of or addiction to daridorexant and should be monitored closely.
Daridorexant (applies to Quviviq) COPD/pulmonary impairment
Moderate Potential Hazard, Moderate plausibility.
Daridorexant is a respiratory depressant and should be used with caution if prescribed to patients with impaired respiratory function. This drug has not been studied in patients with moderate to severe sleep apnea requiring CPAP or in patients with severe chronic obstructive pulmonary disease (COPD).
Daridorexant (applies to Quviviq) depression/suicidal ideation
Moderate Potential Hazard, Moderate plausibility.
Daridorexant can worsen depression and suicidal thoughts and actions and should be used with caution in patients with depression. These patients should be monitored closely and any preventive measures should be taken.
Daridorexant (applies to Quviviq) hepatic dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Daridorexant is not recommended in patients with severe hepatic dysfunction. The maximum recommended dosage in patients with moderate hepatic dysfunction is 25 mg once per night.
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Quviviq drug interactions
There are 680 drug interactions with Quviviq (daridorexant).
Quviviq alcohol/food interactions
There is 1 alcohol/food interaction with Quviviq (daridorexant).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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