Daptomycin Disease Interactions
There is 1 disease interaction with daptomycin.
Daptomycin (applies to daptomycin) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
Renal function tests and CPK should be monitored frequently in patients with renal impairment that are in treatment with daptomycin. Additionally, the success rates of treatment with this drug were lower when used in patients with CrCl <50 mL/min. This should be taken into account when selecting an antibacterial therapy in patients with baseline moderate to severe renal impairment.
- "Product Information. Cubicin (daptomycin)." Cubist Pharmaceuticals Inc (2003):
Daptomycin drug interactions
There are 53 drug interactions with daptomycin.
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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