Skip to Content

Neoloid (castor oil) Disease Interactions

There are 5 disease interactions with Neoloid (castor oil):

Major

Castor oil (applies to Neoloid) dehydration

Major Potential Hazard, High plausibility. Applicable conditions: Hyponatremia, Hypokalemia, Electrolyte Abnormalities

The use of castor oil is contraindicated in patients with dehydration or electrolyte imbalance. Castor oil is hydrolyzed to glycerol and ricinoleic acid within the small intestine. Ricinoleic acid acts on the small intestine to reduce the net absorption of fluid and electrolytes. This altered intestinal permeability caused by castor oil may produce dehydration and electrolyte imbalance.

References

  1. "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc, Minneapolis, MN.
Major

Castor oil (applies to Neoloid) intestinal obstruction

Major Potential Hazard, High plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of castor oil is contraindicated in patients with intestinal obstruction. Fluid and electrolyte build up in the intestinal tract due to castor oil may exacerbate intestinal obstruction.

References

  1. "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc, Minneapolis, MN.
Major

Laxatives (applies to Neoloid) inflammatory bowel disease

Major Potential Hazard, Moderate plausibility.

The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.

References

  1. "Product Information. Fleet Bisacodyl Enema (bisacodyl)." Fleet, Lynchburg, VA.
  2. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc, Woodbridge, NJ.
Major

Laxatives (applies to Neoloid) intestinal obstruction disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.

References

  1. "Product Information. Kondremul (mineral oil)." Bristol-Myers Squibb, Princeton, NJ.
  2. "Product Information. Fleet Bisacodyl Enema (bisacodyl)." Fleet, Lynchburg, VA.
  3. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc, Woodbridge, NJ.
  4. "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet, Lynchburg, VA.
  5. "Product Information. Fleet Babylax (glycerin)." Alcon Laboratorries Inc, Fort Worth, TX.
View all 5 references
Major

Stimulant laxatives (applies to Neoloid) rectal bleeding

Major Potential Hazard, Moderate plausibility.

The use of stimulant laxatives is contraindicated in patients with anal or rectal fissures. These preparations may cause irritation, burning sensation, and proctitis.

References

  1. "Product Information. Fleet Bisacodyl Enema (bisacodyl)." Fleet, Lynchburg, VA.
  2. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc, Woodbridge, NJ.

Neoloid (castor oil) drug interactions

There are 204 drug interactions with Neoloid (castor oil)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.