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Neomycin, polymyxin b, and bacitracin (Ophthalmic)

nee-oh-MYE-sin, pol-ee-MIX-in B SUL-fate, bas-i-TRAY-sin zink

Medically reviewed on September 3, 2018

Commonly used brand name(s)

In the U.S.

  • Neo-Polycin

Available Dosage Forms:

  • Ointment

Therapeutic Class: Antibiotic Combination

Chemical Class: Aminoglycoside

Uses For neomycin, polymyxin b, and bacitracin

Neomycin, polymyxin B, and bacitracin combination antibiotic medicine is used to treat infections of the eye.

Neomycin, polymyxin B, and bacitracin combination is available only with your doctor's prescription.

Before Using neomycin, polymyxin b, and bacitracin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For neomycin, polymyxin b, and bacitracin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to neomycin, polymyxin b, and bacitracin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on neomycin, polymyxin b, and bacitracin have been done only in adult patients, and there is no specific information comparing use of neomycin, polymyxin B, and bacitracin combination in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of neomycin, polymyxin B, and bacitracin combination in the elderly with use in other age groups.

Pregnancy

Pregnancy Category Explanation
All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

Bacitracin

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Neomycin

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking neomycin, polymyxin b, and bacitracin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using neomycin, polymyxin b, and bacitracin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alcuronium
  • Atracurium
  • Cisatracurium
  • Doxacurium
  • Fazadinium
  • Gallamine
  • Hexafluorenium
  • Metocurine
  • Mivacurium
  • Pancuronium
  • Pipecuronium
  • Rapacuronium
  • Rocuronium
  • Tubocurarine
  • Vecuronium

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of neomycin, polymyxin b, and bacitracin

To use:

  • First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A 1-cm (approximately â…“-inch) strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using neomycin, polymyxin B, and bacitracin eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.

To help clear up your infection completely, keep using neomycin, polymyxin b, and bacitracin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

Dosing

The dose of neomycin, polymyxin b, and bacitracin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of neomycin, polymyxin b, and bacitracin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For eye infections:
    • For eye ointment dosage forms:
      • Adults and children—Use a thin strip of ointment in the eyes every three or four hours for seven to ten days.

Missed Dose

If you miss a dose of neomycin, polymyxin b, and bacitracin, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using neomycin, polymyxin b, and bacitracin

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Neomycin, polymyxin b, and bacitracin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  • Itching, rash, redness, swelling, or other sign of irritation not present before use of neomycin, polymyxin b, and bacitracin

After application, eye ointments usually cause your vision to blur for a few minutes.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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