Generic Name: erenumab (e-REN-ue-mab - aooe)
Medically reviewed by Drugs.com. Last updated on Feb 25, 2021.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antimigraine
Pharmacologic Class: Erenumab
Uses for erenumab-aooe
Erenumab-aooe injection is used to prevent migraine headaches.
Erenumab-aooe is available only with your doctor's prescription.
Before using erenumab-aooe
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For erenumab-aooe, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to erenumab-aooe or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of erenumab-aooe injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of erenumab-aooe injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving erenumab-aooe.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of erenumab-aooe. Make sure you tell your doctor if you have any other medical problems, especially:
- Hypertension (high blood pressure)—Use with caution. May make this condition worse.
Proper use of erenumab-aooe
A nurse or other trained health professional will give you erenumab-aooe. It is given through a needle given as a shot under your skin, usually in the stomach, thighs, or upper arm. You or your caregiver may be trained to prepare and inject erenumab-aooe at home. Be sure that you understand how to use the medicine.
If you use erenumab-aooe at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into skin areas that are tender, red, bruised, or hard.
Erenumab-aooe comes with a patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Erenumab-aooe is available in two forms: a a prefilled syringe or an autoinjector.
Check the liquid in the prefilled syringe or autoinjector. It should be clear and colorless to slightly yellow. Do not use the medicine if the liquid is cloudy, discolored, or has particles in it. Do not shake.
Allow the medicine to warm to room temperature for at least 30 minutes before you use it. Do not warm it in any other way.
Do not remove the needle cap from the prefilled syringe or autoinjector until you are ready to use it.
You might not use all of the medicine in each prefilled syringe or autoinjector. Use each prefilled syringe and autoinjector only one time. Do not save an open syringe or autoinjector.
The dose of erenumab-aooe will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of erenumab-aooe. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For injection dosage form (solution):
- For migraine headaches:
- Adults—70 milligrams (mg) injected under the skin once a month. Some patients may be given 140 mg injected under the skin once a month.
- Children—Use and dose must be determined by your doctor.
- For migraine headaches:
If you miss a dose of erenumab-aooe, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Continue to use erenumab-aooe each month from the date of your last dose.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Store in the refrigerator. Do not freeze.
Keep the medicine in its original carton. You may store it at room temperature for up to 7 days after removing it from the refrigerator. Throw away any unused medicine kept at room temperature after 7 days.
Precautions while using erenumab-aooe
It is very important that your doctor check your progress at regular visits to make sure that erenumab-aooe is working properly and to check for unwanted effects.
The needle shield within the white or orange cap of the autoinjector and gray needle cap of the prefilled syringe contains dry natural rubber (a derivative of latex), which may cause allergic reactions in people who are sensitive to latex. Tell your doctor if you have a latex allergy before using erenumab-aooe.
Erenumab-aooe may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using erenumab-aooe.
Erenumab-aooe may increase your risk of having severe constipation, especially when given with medicines that decrease bowel movement. Talk with your doctor if this is a concern for you.
Check with your doctor right away if you have blurred vision, dizziness, nervousness, headache, pounding in the ears, or slow or fast heartbeat. These could be symptoms of high blood pressure.
Erenumab-aooe side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
- Blurred vision
- fast heartbeat
- hives, itching, skin rash
- joint pain, stiffness, or swelling
- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- pounding in the ears
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- slow or fast heartbeat
- tightness in the chest
- troubled breathing or swallowing
- unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- Muscle cramp or spasm
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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More about erenumab
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Support Group
- En Español
- 505 Reviews
- Drug class: CGRP inhibitors
- Other brands
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.