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Medications for Local Anesthesia

Local anesthesia is medicine used to numb a small part of your body while you have a procedure or surgery. It is often used during minor surgery or procedures, such as a biopsy or dental care.

Drugs used for Local Anesthesia

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
lidocaine 5.8 8 reviews for lidocaine to treat Local Anesthesia
Rx/OTC B N
Generic name:
lidocaine topical
Brand names:
Lidocaine Viscous, Xylocaine Jelly, AneCream, Aloe Vera Burn Relief Spray with Lidocaine, Anestacon, Bactine, RectiCare, CidalEaze, DermacinRx Lidotral´╗┐, DermacinRx Lido V Pak, Eha Lotion, Glydo, LidaMantle, Lidopac, LidoRx, Lidosol, Lidotran, Lidotrans 5 Pak, Lidozion, LMX 4, LMX 5, LTA II Kit, Lydexa, Medi-Quik Spray, Moxicaine, RadiaGuard, Regenecare HA Spray, Topicaine, Tranzarel, Xylocaine Topical, Zionodil
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bupivacaine 7.4 7 reviews for bupivacaine to treat Local Anesthesia
Rx C N
Generic name:
bupivacaine systemic
Brand names:
Marcaine, Marcaine Spinal, Marcaine HCl, Sensorcaine, Sensorcaine-MPF
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Marcaine 6.5 2 reviews for Marcaine to treat Local Anesthesia
Rx C N
Generic name:
bupivacaine systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mepivacaine 3.7 10 reviews for mepivacaine to treat Local Anesthesia
Rx C N
Generic name:
mepivacaine systemic
Brand names:
Carbocaine, Polocaine, Scandonest Plain, Polocaine-MPF
Drug class:
local injectable anesthetics
For consumers:
interactions, side effects
For professionals:
Prescribing Information
cocaine 10 1 review for cocaine to treat Local Anesthesia
Rx C 2
Generic name:
cocaine topical
Brand name:
C-Topical Solution
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
articaine / epinephrine 6.2 7 reviews for articaine / epinephrine to treat Local Anesthesia
Rx C N
Generic name:
articaine / epinephrine systemic
Brand names:
Septocaine, Articadent, Zorcaine, Orabloc, Ultacan, Ultacan Forte
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
lidocaine Rate Add review
Rx B N
Generic name:
lidocaine ophthalmic
Brand name:
Akten
Drug class:
ophthalmic anesthetics
For consumers:
dosage, interactions, side effects
Carbocaine 4.3 6 reviews for Carbocaine to treat Local Anesthesia
Rx C N
Generic name:
mepivacaine systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ropivacaine 10 1 review for ropivacaine to treat Local Anesthesia
Rx B N
Generic name:
ropivacaine systemic
Brand names:
Naropin, Naropin Polyamp, Naropin SDV
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
epinephrine / lidocaine 1.0 1 review for epinephrine / lidocaine to treat Local Anesthesia
Rx B N
Generic name:
epinephrine / lidocaine systemic
Brand names:
Xylocaine with Epinephrine, Lignospan, Lignospan Forte, Xylocaine-MPF-Epinephrine
Drug class:
local injectable anesthetics
For consumers:
interactions, side effects
For professionals:
Prescribing Information
Akten Rate Add review
Rx B N
Generic name:
lidocaine ophthalmic
Drug class:
ophthalmic anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cocaine Rate Add review
Rx 2
Generic name:
cocaine nasal
Brand names:
Numbrino, Goprelto
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lidocaine Viscous Rate Add review
Rx B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
Septocaine 6.7 5 reviews for Septocaine to treat Local Anesthesia
Rx C N
Generic name:
articaine / epinephrine systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Naropin Rate Add review
Rx B N
Generic name:
ropivacaine systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Nupercainal 10 1 review for Nupercainal to treat Local Anesthesia
Rx/OTC C N
Generic name:
dibucaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
tetracaine Rate Add review
Rx/OTC C N
Generic name:
tetracaine topical
Brand name:
Pontocaine
Drug class:
topical anesthetics
For consumers:
interactions, side effects
Xylocaine Jelly Rate Add review
Rx/OTC B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
AneCream Rate Add review
OTC B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
Marcaine Spinal Rate Add review
Rx C N
Generic name:
bupivacaine systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Aloe Vera Burn Relief Spray with Lidocaine Rate Add review
OTC B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
Anestacon Rate Add review
OTC B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
Bactine Rate Add review
OTC B N
Generic name:
lidocaine topical
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
chloroprocaine 10 1 review for chloroprocaine to treat Local Anesthesia
Rx C N
Generic name:
chloroprocaine systemic
Brand names:
Nesacaine, Clorotekal, Nesacaine-MPF
Drug class:
local injectable anesthetics
For consumers:
interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
dibucaine 10 1 review for dibucaine to treat Local Anesthesia
Rx/OTC C N
Generic name:
dibucaine topical
Brand name:
Nupercainal
Drug class:
topical anesthetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Learn more about Local Anesthesia

Care guides

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.