Cocaine Nasal Side Effects
Medically reviewed by Drugs.com. Last updated on Jan 30, 2025.
Applies to cocaine nasal: nasal solution.
Important warnings
This medicine can cause some serious health issues
Nasal route (spray)
Warning: Abuse and DependenceCNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence.
Precautions
It is very important that your doctor check your progress closely while receiving this medicine to see if it is working properly. Blood tests may be needed to check for any unwanted effects.
Using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.
This medicine may increase your risk for seizures, especially if you have a history of seizures or heart rhythm problems. Talk to your doctor if you have any concerns about this.
This medicine can increase blood pressure and heart rate. It may also increase your risk of having heart attack. Check with your doctor right away if you have blurred vision, dizziness, nervousness, headache, pounding in the ears, slow or fast heartbeat, chest pain or discomfort, pain or discomfort in the arms, jaw, back, or neck, trouble with breathing, nausea, sweating, or vomiting.
This medicine may cause changes in a woman's menstrual cycle and may reduce ovulation, which can lead to fertility problems. Talk to your doctor if you have concerns.
This medicine may be habit-forming. Tell your doctor if you feel like the nasal area is not numb enough or if the nasal solution is not working well.
Cocaine and its products can be detected in the blood and urine at least 1 week after its last dose.
Check with your doctor before receiving this medicine with medicines that can affect the central nervous system (CNS). The use of stimulants, including caffeine may worsen the side effects of this medicine, such as nervousness, irritability, seizures, or heart rhythm problems. Other medicines that can affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, or muscle relaxants.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of cocaine nasal
Along with its needed effects, cocaine nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking cocaine nasal:
More common side effects
- blurred vision
- dizziness
- headache
- nervousness
- pounding in the ears
- slow or fast heartbeat
Less common side effects
- chest pain or discomfort
- fainting
- fast, pounding, or irregular heartbeat or pulse
- lightheadedness
- unusual tiredness
Incidence not known
- nausea
- pain or discomfort in the arms, jaw, back, or neck
- seizures
- sweating
- vomiting
Other side effects of cocaine nasal
Some side effects of cocaine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- anxiety
For healthcare professionals
Applies to cocaine nasal: nasal solution.
General adverse events
The most common adverse reactions were headache and epistaxis.[Ref]
Nervous system
- Common (1% to 10%): Headache[Ref]
Psychiatric
- Common (1% to 10%): Anxiety
- Frequency not reported: Rapid eye movement sleep decreased, total sleep decreased[Ref]
Cardiovascular
- Frequency not reported: Cardiac activity increased, vasoconstriction[Ref]
Metabolic
- Frequency not reported: Anorexic effect[Ref]
Other
- Frequency not reported: Body temperature increased[Ref]
Respiratory
- Common (1% to 10%): Epistaxis[Ref]
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References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. (2018) "Product Information. Cocaine Hydrochloride Nasal (cocaine nasal)." Genus Lifesciences Inc.
More about cocaine nasal
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- During pregnancy
- Drug class: topical anesthetics
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Further information
Cocaine nasal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.