Bupivacaine Interactions
There are 139 drugs known to interact with bupivacaine, along with 3 disease interactions. Of the total drug interactions, 23 are major, 111 are moderate, and 5 are minor.
- View all 139 medications that may interact with bupivacaine
- View bupivacaine disease interactions (3)
Most frequently checked interactions
View interaction reports for bupivacaine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Adrenalin (epinephrine)
- Amitiza (lubiprostone)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Colace (docusate)
- Cymbalta (duloxetine)
- Dilaudid (hydromorphone)
- Flexeril (cyclobenzaprine)
- Lasix (furosemide)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Morphine Sulfate ER (morphine)
- Norco (acetaminophen / hydrocodone)
- Paracetamol (acetaminophen)
- Percocet (acetaminophen / oxycodone)
- Symbicort (budesonide / formoterol)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Valproate Sodium (valproic acid)
- Vitamin B Complex 100 (multivitamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vitamin K (phytonadione)
- Xanax (alprazolam)
- Zofran (ondansetron)
Bupivacaine disease interactions
There are 3 disease interactions with bupivacaine which include:
Report options
More about bupivacaine
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- Reviews (10)
- Latest FDA alerts (6)
- Side effects
- Dosage information
- During pregnancy
- Drug class: local injectable anesthetics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
