Generic Name: articaine and epinephrine (AR ti kane and EP i NEF rin)
Brand Name: Septocaine
What is Septocaine (articaine and epinephrine)?
Articaine and epinephrine are anesthetics (numbing medicines). They work by blocking nerve signals in your body.
Articaine and epinephrine is a combination medicine used to numb your mouth for a dental procedure.
Articaine and epinephrine may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Septocaine (articaine and epinephrine)?
You should not receive articaine and epinephrine if you have ever had an allergic reaction to any type of numbing medicine.
What should I discuss with my health care provider before receiving Septocaine (articaine and epinephrine)?
You should not receive this medicine if you are allergic to any type of numbing medicine.
To make sure articaine and epinephrine is safe for you, tell your doctor if you have:
a heart rhythm disorder;
low or high blood pressure;
asthma or a sulfite allergy; or
a history of seizures.
FDA pregnancy category C. It is not known whether articaine and epinephrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether articaine and epinephrine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is Septocaine (articaine and epinephrine)given?
Articaine and epinephrine is given as an injection that is usually placed into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgical setting.
What happens if I miss a dose?
Since articaine and epinephrine is given as needed before a dental procedure, you are not likely to be on a dosing schedule.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or slow heart rate.
What should I avoid after receiving Septocaine (articaine and epinephrine)?
This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.
Septocaine (articaine and epinephrine) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling or puffiness of your face, lips, tongue, or throat.
Tell your caregivers right away if you have:
weak or shallow breathing;
a slow heart rate;
a light-headed feeling, like you might pass out;
blurred vision, ringing in your ears; or
anxiety, confusion, restless feeling, or tremors.
Call your doctor or dentist at once if you have any swelling, pain, or heavy bleeding after your procedure.
Common side effects may include:
tongue pain or swelling, red or swollen gums;
mild swelling in your face;
numbness and tingling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Septocaine (articaine and epinephrine)?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with articaine and epinephrine, especially:
an antidepressant--amitriptylline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, trimipramine;
antipsychotic medication--chlorpromazine, droperidol, fluphenazine, haloperidol, perphenazine; or
an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
This list is not complete. Other drugs may interact with articaine and epinephrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Septocaine (articaine / epinephrine)
Related treatment guides
Where can I get more information?
- Your dentist or pharmacist can provide more information about articaine and epinephrine.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.
Date modified: October 14, 2016
Last reviewed: September 17, 2014