Comparing Xgeva vs Zoledronic Acid
| Xgeva (denosumab) | Zoledronic acid |
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| Xgeva (denosumab) | Zoledronic acid |
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Prescription only
Xgeva is an injection that is administered every four weeks to prevent bone fractures in people with certain types of cancer or to lower calcium levels in people with high calcium levels caused by... View more |
Prescription only
Zoledronic acid strengthens bones and is used to manage several different bone-related conditions. Zoledronic acid injection (Reclast, 5 mg/100 mL) is used to treat and prevent postmenopausal or... View more |
Related suggestions Hypercalcemia of Malignancy
Popular comparisons
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| More about Xgeva (denosumab) | More about Zoledronic acid | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Xgeva has an average rating of 5.6 out of 10 from a total of 10 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 40% reported a negative effect. |
Zoledronic acid has an average rating of 5.0 out of 10 from a total of 421 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 45% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Xgeva side effects |
View all Zoledronic acid side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Xgeva prices |
View all Zoledronic acid prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other denosumab brands include: Bomyntra, Conexxence, Jubbonti, Osenvelt, Ospomyv, Prolia, Stoboclo, Wyost, Xbryk View more | Aclasta, Reclast, Zometa | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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609.6 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 311 drugs are known to interact with Xgeva:
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A total of 126 drugs are known to interact with Zoledronic acid:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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June 01, 2010 |
December 28, 2015 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Prolia
Prolia (denosumab) is an injection that is administered subcutaneously (under the skin) once every ...
Reclast
Reclast (zoledronic acid) is used to treat osteoporosis in women after menopause and also to treat ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Zometa
Zometa is used to treat high blood levels of calcium caused by cancer and multiple myeloma. Learn ...
Jubbonti
Jubbonti (denosumab-bbdz) is an injection that is administered subcutaneously (under the skin) once ...
Aclasta
Aclasta (zoledronic acid) inhibits the release of calcium from bones and is used to treat Paget's ...
Wyost
Wyost (denosumab-bbdz) is an injection that is administered subcutaneously (under the skin) by a ...
Zoledronic acid
Zoledronic acid is used for hypercalcemia of malignancy, osteolytic bone lesions of multiple ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.