Siponimod Alternatives Compared
| Siponimod | Avonex | Vumerity |
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| Siponimod | Avonex (interferon beta-1a) | Vumerity (diroximel fumarate) |
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Prescription only
Prescribed for Multiple Sclerosis. siponimod may also be used for purposes not listed in this medication guide. |
Prescription only
Avonex is a type of interferon beta-1a that may be used to treat adults with multiple sclerosis (MS). It is administered intramuscularly once weekly into the upper thigh. Headache, flu-like... View more |
Prescription only
Vumerity (generic name: diroximel fumarate) is an oral prescription medicine indicated for the treatment of relapsing forms of multiple sclerosis (MS) in adults. It is given as a twice-daily medicine... View more |
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| More about Siponimod | More about Avonex (interferon beta-1a) | More about Vumerity (diroximel fumarate) | ||||||||
| Ratings & Reviews | ||||||||||
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Siponimod has an average rating of 7.3 out of 10 from a total of 9 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 29% reported a negative effect. |
Avonex has an average rating of 7.2 out of 10 from a total of 46 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 22% reported a negative effect. |
Vumerity has an average rating of 9.4 out of 10 from a total of 6 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||
| Side Effects | ||||||||||
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See also: siponimod side effects in more detail. |
See also: Avonex side effects in more detail. |
See also: Vumerity side effects in more detail. |
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| Generic Availability | ||||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Vumerity prices |
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| Dosage Forms Available | ||||||||||
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N/A |
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| Brand Names | ||||||||||
| Mayzent | Other interferon beta-1a brands include: Avonex Pen, Avonex Prefilled Syringe, Rebif, Rebif Rebidose |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||
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30 hours |
3 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 709 drugs are known to interact with siponimod:
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A total of 334 drugs are known to interact with Avonex:
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A total of 617 drugs are known to interact with Vumerity:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
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March 26, 2019 |
May 17, 1996 |
October 29, 2019 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.