Skip to main content
Print

Sildenafil Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Sildenafil Cialis Viagra
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Sildenafil Cialis (tadalafil) Viagra (sildenafil)
Prescription only

Sildenafil is used to treat erectile dysfunction (ED) and to reduce blood pressure in pulmonary arterial hypertension (PAH). It is taken when needed for ED and daily for PAH. A headache, stomach... View more

Prescription only

Cialis is used to treat erectile dysfunction (ED) and to reduce symptoms of benign prostatic hyperplasia (BPH). One 'as needed' tablet lasts for 36 hours or Cialis is available as a lower dosage... View more

Prescription only

Viagra is used to treat erectile dysfunction (ED), but will not have any effect in the absence of sexual stimulation. A headache, stomach upsets, and flushing are the main side effects. Prescribed... View more

More about Sildenafil More about Cialis (tadalafil) More about Viagra (sildenafil)
Generic Status

Lower-cost generic is available

Lower-cost generic is available

Lower-cost generic is available
Ratings & Reviews

Sildenafil has an average rating of 8.2 out of 10 from a total of 493 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 13% reported a negative effect.

Cialis has an average rating of 8.5 out of 10 from a total of 549 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 9% reported a negative effect.

Viagra has an average rating of 8.6 out of 10 from a total of 258 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 9% reported a negative effect.

View all 493 reviews

View all 549 reviews

View all 258 reviews

Drug Class
Side Effects

Commonly reported side effects include:

  • dyspepsia
  • headache
  • visual disturbance
  • flushing

See also: sildenafil side effects in more detail.

Common side effects include:

  • dyspepsia
  • headache

See also: Cialis side effects in more detail.

Common side effects include:

  • dyspepsia
  • headache
  • visual disturbance
  • flushing

See also: Viagra side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 10 tablet
Dosage 20 mg
Per Unit* $1.82
Cost* $18.22

View all sildenafil prices

Quantity 30 tablet
Dosage 20 mg
Per Unit* $73.50
Cost* $2,205.01

View all Cialis prices and generic prices

Quantity 30 tablet
Dosage 100 mg
Per Unit* $87.99
Cost* $2,639.84

View all Viagra prices and generic prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Form(s) Available
  • Intravenous solution
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet
  • Oral tablet
Brand Names
Liqrev, Revatio, Viagra Other tadalafil brands include: Adcirca, Alyq, Tadliq Other sildenafil brands include: Liqrev, Revatio
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

4 hours

17.5 hours

4 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
B
Category B No proven risk in humans

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
Drug Interactions

A total of 326 drugs are known to interact with sildenafil:

  • 37 major drug interactions (133 brand and generic names)
  • 285 moderate drug interactions (892 brand and generic names)
  • 4 minor drug interactions (42 brand and generic names)

A total of 296 drugs are known to interact with Cialis:

  • 29 major drug interactions (114 brand and generic names)
  • 167 moderate drug interactions (494 brand and generic names)
  • 100 minor drug interactions (280 brand and generic names)

A total of 326 drugs are known to interact with Viagra:

  • 37 major drug interactions (133 brand and generic names)
  • 285 moderate drug interactions (892 brand and generic names)
  • 4 minor drug interactions (42 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • If you are receiving therapy with sildenafil you should avoid the regular consumption of large... View more
  • Sildenafil can lower blood pressure, and combining it with alcohol may further increase this... View more
  • Tadalafil can lower blood pressure, and combining it with alcohol may further increase this effect... View more
  • If you are receiving therapy with sildenafil you should avoid the regular consumption of large... View more
  • Sildenafil can lower blood pressure, and combining it with alcohol may further increase this... View more
Disease Interactions
First Approval Date

March 27, 1998

November 21, 2003

March 27, 1998
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Compare Drugs

To view a report comparing 3 (or more) medications, please sign in or create an account.

Create an account Sign In