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Cialis (tadalafil) Drug Interactions

A total of 355 drugs are known to interact with Cialis (tadalafil).

  • 11 major drug interactions
  • 190 moderate drug interactions
  • 154 minor drug interactions

Show all medications in the database that may interact with Cialis (tadalafil).

Check for interactions

Type in a drug name to check for interactions with Cialis (tadalafil).

Most frequently checked interactions

View interaction reports for Cialis (tadalafil) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • alfuzosin (Uroxatral)
  • amlodipine (Norvasc)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, DisperMox, Moxatag, Biomox, Wymox, Moxilin)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • caffeine (Vivarin, Caffedrine, Jet Alert Regular Strength, Jet Alert Maximum Strength, Stay Awake, Alert, Diurex Ultra, Valentine, NoDoz, Jet Alert Double Strength, ConRx Alert, Pep-Back ReCharge, Pep-Back Peak Performance, Keep Alert, Verv, Stat Awake, Stay Alert, NoDoz Maximum Strength, Wakespan, Lucidex, Diurex Maximum Relief Water Caps, Pep-Back Ultra, Cafcit, 357 HR Magnum, Enerjets, Fastlene, Keep Going, Molie, Overtime)
  • Crestor (rosuvastatin)
  • Eliquis (apixaban)
  • finasteride (Proscar, Propecia)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Flomax (tamsulosin)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • grapefruit
  • hydrochlorothiazide (HydroDIURIL, Microzide, Oretic, Esidrix, Ezide, Diaqua, Aquazide H, Hydro Par, Carozide, Loqua)
  • L-Arginine (arginine)
  • Lipitor (atorvastatin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Oxyfast, Oxecta, RoxyBond, Percolone, Dazidox, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • simvastatin (Zocor, FloLipid)
  • tamsulosin (Flomax)
  • testosterone (AndroGel, Androderm, Depo-Testosterone, Xyosted, Testim, Axiron, Fortesta, Testopel, Aveed, Delatestryl, Testopel Pellets, Natesto, Jatenzo, Testamone-100, Vogelxo, Testro AQ, Everone, Andro-Cyp 100, Testo-100, Striant, FIRST-Testosterone, Testoderm, Testolin, Depotest, Virilon IM, Delatest, Andro LA 200, Andro-Cyp 200, Depandro 100, Duratest, Durathate 200, Histerone, Meditest, Testro, Testro-LA, FIRST-Testosterone MC)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, ConZip, Ultram ER, Zydol, Tramahexal, Zamadol, Ryzolt, Tramal SR, Larapam SR, GenRx Tramadol, Tramahexal SR, Tramedo, Zydol XL, Rybix ODT, Ultram ODT)
  • Viagra (sildenafil)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Xarelto (rivaroxaban)
  • Zoloft (sertraline)

Cialis (tadalafil) alcohol/food interactions

There is 1 alcohol/food interaction with Cialis (tadalafil)

Cialis (tadalafil) disease interactions

There are 9 disease interactions with Cialis (tadalafil) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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