Comparing Protopic vs Zoryve
| Protopic (tacrolimus) | Zoryve (roflumilast) |
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| Protopic (tacrolimus) | Zoryve (roflumilast) |
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Prescription only
Prescribed for Atopic Dermatitis. Protopic may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Plaque Psoriasis. Zoryve may also be used for purposes not listed in this medication guide. |
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| More about Protopic (tacrolimus) | More about Zoryve (roflumilast) | ||||||||
| Ratings & Reviews | |||||||||
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Protopic has an average rating of 7.1 out of 10 from a total of 95 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 23% reported a negative effect. |
Zoryve has an average rating of 8.6 out of 10 from a total of 49 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Protopic side effects |
View all Zoryve side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zoryve prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other tacrolimus brands include: Tacrus | Other roflumilast brands include: Zoryve Foam | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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21.2 hours |
9.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 1 drugs are known to interact with Protopic:
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A total of 103 drugs are known to interact with Zoryve:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||
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December 08, 2000 |
July 29, 2022 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.