Comparing Ocrevus vs Tecfidera

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Ocrevus ocrelizumab

Tecfidera dimethyl fumarate

Ocrevus is a CD20 monoclonal antibody that causes B-cells to self-destruct or disintegrate, reducing inflammation in people with MS. After an initial loading dose, it is given by IV infusion every... View more

Tecfidera is a disease-modifying drug that may be used to reduce disease progression and relapses in people with multiple sclerosis. Flushing and gastrointestinal effects are the most common initial... View more

Prescription only

Ratings & Reviews

View all 117 reviews

View all 90 reviews

Drug Class

CD20 monoclonal antibodies

Selective immunosuppressants

Side Effects

See the full Ocrevus side effects document.

See the full Tecfidera side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	10 mL
Dosage	300 mg/10 mL
Per Unit^*	$1,778.93
Cost^*	$17,789.25

View all Ocrevus prices

Quantity	14 delayed release capsule
Dosage	120 mg
Per Unit^*	$144.68
Cost^*	$2,025.57

View all Tecfidera prices and generic prices

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Generic Availability

Yes

Dosage Form(s) Available

Intravenous solution

Oral delayed release capsule

Brand Names

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

624 hours

1 hour

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Summary unavailable.

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 331 drugs are known to interact with Ocrevus:

33 major drug interactions (86 brand and generic names)
291 moderate drug interactions (887 brand and generic names)
7 minor drug interactions (33 brand and generic names)

A total of 317 drugs are known to interact with Tecfidera:

38 major drug interactions (96 brand and generic names)
279 moderate drug interactions (857 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

March 28, 2017

March 27, 2013

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer