Comparing Neupro vs Rytary

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Neupro (rotigotine)	Rytary (carbidopa / levodopa)	Enter another drug to compare

Neupro (rotigotine)

Rytary (carbidopa / levodopa)

Prescription only

Prescribed for Restless Legs Syndrome, Parkinson's Disease. Neupro may also be used for purposes not listed in this medication guide.

Prescription only

Rytary is an extended-release (long-lasting) medication that may be used for the treatment of Parkinson's disease that is available in four different strengths: Rytary 23.75/95, Rytary 36.25/145... View more

More about Neupro (rotigotine)

More about Rytary (carbidopa / levodopa)

Ratings & Reviews

Neupro has an average rating of 7.6 out of 10 from a total of 73 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 12% reported a negative effect.

Rytary has an average rating of 6.2 out of 10 from a total of 31 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 32% reported a negative effect.

View all 73 reviews

View all 31 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Itching (12.3%)
Drowsiness (9.6%)
Insomnia (5.5%)
Nausea (4.1%)
Tremors (4.1%)

View all Neupro side effects

View all Rytary side effects

Drug Class

Dopaminergic antiparkinsonism agents

Dopaminergic antiparkinsonism agents

Generic Availability

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	30 film, extended release
Strength	1 mg/24 hr
Per unit^*	$31.08
Cost^*	$932.29

View all Neupro prices

Quantity	100 capsule, extended release
Strength	23.75 mg-95 mg
Per unit^*	$4.54
Cost^*	$453.54

View all Rytary prices

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Dosage Forms

Transdermal film, extended release

Oral capsule, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

7 hours

2.3 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 256 drugs are known to interact with Neupro:

40 major drug interactions (135 brand and generic names)
215 moderate drug interactions (1042 brand and generic names)
1 minor drug interactions (3 brand and generic names)

A total of 520 drugs are known to interact with Rytary:

50 major drug interactions (158 brand and generic names)
459 moderate drug interactions (3233 brand and generic names)
11 minor drug interactions (111 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of rotigotine such as dizziness, drowsiness... View more

Alcohol can increase the nervous system side effects of levodopa such as dizziness, drowsiness, and... View more

Disease Interactions

First Approval Date

May 09, 2007

January 07, 2015

WADA Class View classifications

N/A

More Information

Patient Resources

Neupro uses

Rytary uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Neupro vs Rytary

See also:

Sinemet

Cogentin

Taltz

Requip

Mirapex

Rytary

Azilect

Exelon

Crexont

Horizant

Further information

Comparing Neupro vs Rytary

See also:

Further information

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